Projects

• All of them
• Co-Founder of INFECT

Projects

• Bacterial Quantitative Fitness Analysis (BaQFA)
• Epidemiology of Infectious Diseases
• Co-Founder of INFECT

Project

• MRSA/MSSA eradications with commensals

‍Funding: Gebert Rüf Stiftung

Collaboration: Prof. Lucio Isa, ETHZ, PD Markus Hilty, University of Bern

Projects

• Nasal bacterial microbiota composition - longitudinal stability and consortia
• HISteria: Role of histamine—whether directly secreted by the airway microbiota or induced by bacteria (host cells) —in the pathophysiology of respiratory allergies

Own Funding: GRC Career Grant; USZ Innopool Grant; Swiss Life Foundation

Projects

• Commensals in human upper respiratory tract and host innate immunity: Modulating functional capacity of innate immune response by nasal commensals against pathobionts

Joint supervision with Dr. S. Mairpady Shambat and Prof. A. Zinkernagel

• The bacterial microbiota in burn patients – understanding microbial evolution under antibiotic selection pressure for future therapeutic and preventive approaches

Funding: Béatrice-Ederer-Weber Foundation; FreeNovation

‍Collaboration: Dr. Philipp Bühler, USZ, Dr. Srikanth Mairpady Shambat, USZ, Prof. Rolf Kümmerli, UZH

Projects

• Development of a translational therapy using commensal bacteria (Dolosigranulum pigrum and Corynebacterium spp.) to prevent and treat colonization by major human pathogens
  
  • Evaluation of therapeutic effects against Streptococcus pneumoniae and Staphylococcus aureus in a 3D airway tissue model
  • Investigation of pathogen survival and host-pathogen interactions in rodent colonization models
  • Identification of in vivo transcriptomic networks involved in commensal-pathogen-host dynamics

Projects

• Chlorhexidine susceptibility in multidrug resistant pathogens
• Study physician FENDER Study
• Burn Skin Cohort Study

Project

• Association of V'CO2 and bacterial superinfections in mechanically ventilated COVID-19 patients

Projects

• Characterization of inhibition factors by commensal bacteria of the nasal microbiome

Projects

• Isolation of commensal-produced inhibitory factors
• Single Cell Analysis of Microbes on Agar Pads

Projects

• Investigation of characteristics of invasive and colonizing bacteria under antimicrobial treatment in infective endocarditis
• Investigation of impact of different treatment options on the nasal and gut microbiome in infective endocarditis
• The PRospective Swiss EndoCarditis COhort and Platform (PROSECCO)

Joint supervision with Prof. A. Zinkernagel and Prof. Barbara Hasse

Funding: SNSF Grant 219351

Projects

• Development of a comparative genomics platform containing bacterial genomes
• Facilitation of epidemiological studies through genomic data integration
• Focus on outbreak prediction and bacterial surveillance systems

Joint supervision with Prof. A. Zinkernagel and Prof. Roger D. Kouyos

‍

Project

• Multidrug-Resistant Pseudomonas aeruginosa

Project

• Vancomycin-resistant Enterococci detection, novel typing methods

‍Collaboration: PD Alban Ramette, University of Bern

Funding: Innopool USZ (to Thomas C. Scheier)

Project

• Immunopolyp (collaboration with Prof. Michael Soyka, PD Urs Steiner)

Funding: OPO-Foundation (OPO-Stiftung)